Precision Medicine, Genetic Testing & Targeted Therapies are Expanding Oncology Treatment Opportunities

This is an in depth review of the American Society of Clinical Oncology’s (ASCO) panel on their State of Cancer in America annual report released January 31st, 2018. MyOncoPath is dedicated to providing cancer patients and oncology providers with genetic counseling for somatic and diagnostic genetic testing to expand access to precision medicine.

ASCO State of Cancer Care Logo

ASCO Precision Medicine Panel 1 Image Read more

FDA approves first treatment for breast cancer with a certain inherited genetic mutation

The U.S. Food and Drug Administration today expanded the approved use of Lynparza (olaparib tablets) to include the treatment of patients with certain types of breast cancer that have spread (metastasized) and whose tumors have a specific inherited (germline) genetic mutation, making it the first drug in its class (PARP inhibitor) approved to treat breast cancer, and it is the first time any drug has been approved to treat certain patients with metastatic breast cancer who have a “BRCA” gene mutation. To find out if you or your patients carry the BRCA gene mutation and if they are eligible for Lynparza or other personalized treatment options contact MyOncoPath’s genetic counselors. Patients are selected for treatment with Lynparza based on an FDA-approved genetic test, called the BRACAnalysis CDx.

Breast Cancer Stats for BRCA Genetic Mutation & Mammograms

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Keytruda Immunotherapy FDA Approval – Cancer Treatment for Tumors with Specific Genetic Markers

In May 2017 the FDA granted accelerated approval to an immunotherapy cancer treatment for patients whose cancers have a specific genetic feature (biomarker). This approval marked the first time the FDA approved a cancer treatment based on a common biomarker rather than the location in the body where the tumor originated.

Keytruda is a cancer immunotherapy drug, which works with a cancer patients immune system to help fight cancer. It is not a chemotherapy or radiation therapy. This cancer fighting immunotherapy works on specific types of cancers, including melanoma (skin cancer), a type of lung cancer called non–small cell lung cancer (NSCLC), classical Hodgkins lymphoma, head and neck squamous cell cancer, advanced urothelial bladder cancer, and  microsatellite instability-high (MSI‑H) cancers. The latest FDA approval is on Keytruda is specifically for the MSI-H or dMMR genetic marker. Read more

Immunotherapy Cancer Treatment Options Available Through Genetic Testing

 An Immunotherapy targets a cancer patient’s immune system with the goal of activating the immune system to attack cancer cells, where as a chemotherapy, generally kills cells that are reproducing (hence some of the side effects like hair loss are common).  Immunotherapy is a type of cancer treatment that boost’s the body’s immune defenses to fight […]